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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQP1
All Species:
29.7
Human Site:
S167
Identified Species:
54.44
UniProt:
P29972
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29972
NP_932766.1
269
28526
S167
R
R
R
D
L
G
G
S
A
P
L
A
I
G
L
Chimpanzee
Pan troglodytes
XP_519026
269
28548
S167
R
R
R
D
L
G
G
S
A
P
L
A
I
G
L
Rhesus Macaque
Macaca mulatta
XP_001084411
269
28522
S167
R
R
R
D
L
G
G
S
A
P
L
A
I
G
L
Dog
Lupus familis
XP_543678
271
28842
F166
T
P
A
L
S
I
G
F
S
V
A
L
G
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q02013
269
28775
S167
R
R
R
D
L
G
G
S
A
P
L
A
I
G
L
Rat
Rattus norvegicus
P29975
269
28838
S167
R
R
R
D
L
G
G
S
A
P
L
A
I
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521059
168
18146
G72
G
S
A
P
L
A
I
G
L
S
V
A
L
G
H
Chicken
Gallus gallus
NP_001034542
270
28478
S168
R
R
N
D
V
S
G
S
A
P
L
A
I
G
L
Frog
Xenopus laevis
NP_001085391
274
29077
S174
R
R
N
D
V
S
G
S
A
P
L
A
I
G
L
Zebra Danio
Brachydanio rerio
NP_996942
260
27399
G164
G
S
A
P
L
A
I
G
L
S
V
C
L
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Z7
245
25557
L149
E
A
L
I
T
F
I
L
V
F
V
V
K
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XF58
285
29817
T178
L
A
A
E
I
I
G
T
F
V
L
V
Y
T
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43286
287
30456
T178
L
A
A
E
I
I
G
T
F
V
L
V
Y
T
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.1
44.6
N.A.
94
93.3
N.A.
50.9
85.5
74.8
59.4
N.A.
36.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.5
63
N.A.
95.5
95.1
N.A.
58.3
91.8
86.8
75
N.A.
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
20
80
80
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
33.3
86.6
86.6
26.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
41.8
N.A.
N.A.
Protein Similarity:
N.A.
55.4
N.A.
56.1
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
39
0
0
16
0
0
54
0
8
62
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
54
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
16
8
0
0
0
0
0
% F
% Gly:
16
0
0
0
0
39
77
16
0
0
0
0
8
70
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
16
% H
% Ile:
0
0
0
8
16
24
24
0
0
0
0
0
54
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
16
0
8
8
54
0
0
8
16
0
70
8
16
0
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
16
0
0
0
0
0
54
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
54
54
39
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
0
0
8
16
0
54
8
16
0
0
0
0
0
% S
% Thr:
8
0
0
0
8
0
0
16
0
0
0
0
0
16
0
% T
% Val:
0
0
0
0
16
0
0
0
8
24
24
24
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _